Minor salivary gland tumours of upper aerodigestive tract. Presentation is key to diagnosing salivary gland disorders. Review of salivary gland neoplasms pubmed central pmc. Current concepts in diagnosis of unusual salivary gland tumors. Salivary gland tumors are rare types of tumors that begin in the salivary glands. Still in the us, carcinomas of the major salivary glands comprise 11% of oropharyngeal neoplasms. Tests that examine the head, neck, and the inside of the mouth are.
Palate, upper lip, cheek and floor of mouth are presented. Adenoid cystic carcinoma was the commonest lesion59% followed by adenocarcinoma29% and mucoepidermoid carcinoma12%. Tumours can occur in both the major and minor salivary glands. Salivary gland tumors symptoms and causes mayo clinic. Salivary gland tumors are rare, and information on management of locoregional and metastatic disease is based on retrospective series and phase ii trials, most commonly in acc. Salivary glands make saliva, which aids in digestion, keeps your mouth moist and supports healthy teeth. Masses of the salivary gland region in children pediatric. Conservative and functional surgery in the treatment of. Salivary carcinomas are a rare collection of neoplasms that account for roughly 3% to 5% of all head and neck malignancies.
Sep 01, 2002 salivary gland tumours are a relatively rare and morphologically diverse group of lesions. Four cases of minor salivary gland tumours at different sites i. Salivary gland tumors sgts are rare neoplasms accounting for 0. Fine needle aspiration fna of salivary gland tumours is still the favoured initial approach as it results in good sensitivity and specificity. Mucous and salivary gland tumourspart i the british. They occur at a rate of about 1 case per 100,000 people per year in the united states. Longterm results are related to the grade of the cancer. Malignant sgts represent 6% of head and neck cancers and 0. In the nasal cavity or paranasal sinus they cause nasal obstruction or sinusitis. Salivary gland tumours salivary gland tumours speight, pm.
Malignant minor salivary gland tumours of the nose and. Saliva has enzymes that help digest food and antibodies that help protect against infections of the mouth and throat. Salivary gland cancer is a rare disease in which malignant cancer cells form in the tissues of the salivary glands. Sep 28, 2017 salivary gland cancers malignant salivary gland tumors there are many types of salivary gland cancers. Second primary cancers in patients with tumours of the. In a series of patients drawn from the birmingham regional cancer registry england with tumours of the salivary glands, a significant excess of second primary tumours was observed. The tumors can arise in about 80% in parotid gland, 15% in submandibular gland and 5% in the sublingual and minor salivary gland. Pleomorphic adenoma of minor salivary gland in the. Salivary gland tumors can begin in any of the salivary glands in your mouth, neck or throat. Oct 16, 2018 intraoral minor salivary gland tumors constitute both benign and malignant tumors of the minor salivary glands.
Salivary gland tumours are among the most common tumours in the oral and maxillofacial regions. Salivary gland tumours most often present as painless enlarging masses. Distribution of cancers by anatomical regions was different and presented in table 1 and table 2. Salivary gland cancers malignant salivary gland tumors there are many types of salivary gland cancers. We hypothesized that the distribution of patients with salivary gland tumors could vary according to country, gender, age and tumor specificity. Tumors were more common in the major salivary glands 73. Little is known about the total incidence of salivary gland tumours as most benign tumours go unrecorded in national cancer registries. Salivary gland tumors are a comparatively rare disorder, accounting for only 1% of all neoplasms of the head and neck region. A rare case of a minor salivary gland pleomorphic adenoma of the parapharyngeal space is reported. Pleomorphic adenoma pa is the most common benign tumor of salivary glands. Worldwide annual incidence of salivary gland tumours varies from 0. Multidisciplinary management of salivary gland cancers. Retrospective study of 124 cases of salivary gland tumors.
Meenakshi suri, pathologist srl diagnostics, b 37, rama park, delhi110059 abstract. The minor salivary gland tumors msgts may be present in individuals of a wide age range including children and adults. This is the official guideline endorsed by the specialty associations involved in the care of head and neck cancer patients in the uk. Feb 16, 2012 tumours can occur in both the major and minor salivary glands. Salivary gland tumors are relatively uncommon and account for approximately 36% of all neoplasms of the head and neck. Diagnostic significance of fnac in salivary gland tumours. For malignant tumors, treatment is with excision and radiation. Salivary gland tumours are rare and have very wide histological heterogeneity, thus making it difficult to generate high level evidence. Being exposed to certain types of radiation may increase the risk of salivary cancer. Salivary gland tumours are a relatively rare and morphologically diverse group of lesions. These are commonly seen in the cheek, palate, and lips. The principal hurdle in their management lies in the difficulty in distinguishing benign from malignant tumours.
After the injection of 90 ml of contrast material at a. As a general rule in clinical practice, the smaller the salivary gland is, the more likely the tumour is malignant. Most pas occur in the parotid 80%, followed by the submandibular gland 10% and minor salivary and sublingual glands 10%. Aug 15, 2019 salivary gland tumours are among the most common tumours in the oral and maxillofacial regions. Salivary gland tumours are a morphologically and clinically diverse group of neoplasms, which may present considerable diagnostic and management challenges to the pathologist or surgeon. Normal salivary glands are made up of many different kinds of cells, and tumors can start in any of these cell types. Intraoral minor salivary gland tumors constitute both benign and malignant tumors of the minor salivary glands. Multiple tumours of the parotid gland the journal of. The tissue material for the study was obtained from various outpatients and inpatients admitted in ent and surgery department in mlb medical college. Ultrasound is the ideal initial investigation for evaluating submandibular masses and lesions in the superficial lobe of parotid, particularly as it is readily combined with fnac. Primary pleomorphic adenoma of minor salivary gland in the.
Read more about osteoclast like giant cell tumour of the salivary gland. Although most clinicians and pathologists will have encountered the more common benign neoplasms, few have experience of the full range of salivary cancers, which are best managed in specialist centres. Salivary gland cancers are named according to which of these cell types they most look like when seen under a microscope. Minor salivary gland lesions in the mucosa of oral cavity, pharynx and tracheobronchial tree, are also not accessible by conventional ultrasound. The incidence of the tumors is summarized in table 3, table 3 continue. Jul 31, 2015 minor salivary gland tumours vary according on the site of origin painless masses on the palate or floor of the mouth are the most common form but laryngeal salivary gland tumours can produce airway obstruction, dysphagia, or hoarseness. A painless salivary mass is the most common sign and is evaluated by fineneedle aspiration biopsy.
Salivary gland malignancies are uncommon, representing 16% of head and neck malignancies and 0. Submandibular gland pas usually manifest in the submandibular area as a painless hard mass. Present paper describes our experience of treating26 cases of malignant minor salivary gland tumours involving the nasal cavity and the paranasal sinuses198084. Of 221 patients with salivary gland tumours, 56 patients with msgt were selected. The parapharyngeal space is very rare site for this tumour. Still in the us, carcinomas of the major salivary glands comprise 11% of. Around 50% of the tumours found in the submandibular glands are benign. Oct 26, 2018 salivary gland tumors most commonly occur in the parotid gland, accounting for nearly 85 percent of all salivary gland tumors.
The commonest histological diagnoses were pleomorphic adenoma n 776 and adenolymphoma n. Although most clinicians and pathologists will have encountered the more common benign neoplasms, few have experience of the full range of salivary cancers, which are best. As a general rule in clinical practice, the smaller the. The most common tumour was found at parotid gland in 154 62. Approximately 25 percent of parotid tumors are cancerous malignant. M aking a diagnosis of a salivary gland disorder can be difficult. Most are located in the parotid glands and most are benign. Signs of salivary gland cancer include a lump or trouble swallowing. According to data from the seven main dental schools in china, among 69 902 cases of oral and. The mucous and salivary gland group of tumours has been defined 1 as being made up partly of tumours of the large salivary glands of the mouth and partly of similar tumours which occur particularly within or in the neighbourhood of mucous membranes with serous, seromucous or mucous glands.
The histopathologic diagnosis was obtained by means of surgical resection or biopsy in all patients. Common presentations, such as a painful or swollen gland, can be caused by numerous disorders of strikingly variable severity and consequences, including inflammatory, infectious, and neoplastic conditions, for which treatment can differ significantly, and referral for specialty care is sometimes necessary. Salivary gland tumours are rare with an overall incidence in the western world of about 2. Cancers of the major salivary gland journal of oncology. Current aspects of salivary gland tumors a systematic.
Sixtyfour patients with major salivary gland tumors underwent twophase helical ct. Our information about salivary gland cancers does not cover benign tumors salivary gland cancers malignant salivary gland tumors there are many types of salivary gland cancers. Pleomorphic adenoma is of rare occurrence in parapharangeal space. Sep 10, 2002 salivary gland tumours are a morphologically and clinically diverse group of neoplasms, which may present considerable diagnostic and management challenges to the pathologist or surgeon. The commonest of these tumours is the socalled mixed tumour, and although for a long time similar tumours have been known to occur in situations other than the main salivary glands, notably in the head and neck region, e. Within the parotid gland 75 80% of tumours are benign. Majority of tumours occurring in minor salivary gland are malignant. Between 1947 and 1992, 1403 patients with 1432 salivary gland tumours were treated at the christie hospital, manchester. These cancers can occur in people of almost any age, but they become more common as people get older.
Salivary gland malignancies are rare entities that contribute to approximately 5% of head and neck malignancies. Diagnostic significance of fnac in salivary gland tumours a. The cytopathology of salivary glands presents major challenges due to the heterogeneity of benign and malignant neoplasms, which is reflected in the large range of who 2017 classifications. This study provides an uptodate overview of the distribution of salivary gland tumors in relation to sex, land of treatment, localization of the tumor in the mouths, and benignmalignant disease of this type of tumor.
Diagnostic significance of fnac in salivary gland tumours a cytohistologic correlation dr. Salivary gland tumors msd manual professional edition. World literature suggests parapharyngeal space lesions account for only 0. Review of literature, clinical features, pathology, radiological findings and treatment of these tumours are discussed. Salivary gland tumours are a common clinical dilemma and imaging plays a useful role in establishing diagnosis, evaluating extent of local and distant involvement. The aim of this retrospective study of 56 patients with minor salivary gland tumours msgts of the upper aerodigestive tract is to present demographic features, distribution of tumours as well as methods and results of treatment performed in our institution over a 10year period. Treatment for salivary gland tumors often involves surgery.
To study the incidence of salivary gland tumors in bundelkhand region. Treatments for salivary gland tumors may also include radiation therapy and chemotherapy. Age distribution of patients with salivary gland tumours between the gender. Salivary gland cancers are not very common, making up less than 1% of cancers in the united states. Most salivary gland tumors are benign and occur in the parotid glands. Recent study suggests that mr spectroscopy may differentiate malignant and benign salivary gland tumours as well as distinguishing warthins tumor from pleomorphic adenoma. Benign tumours of minor salivary glands springerlink. Seroustype acini of a parotid gland with dense secretory granules histologic section of a submaxillary gland. Portion of a parotid gland demonstrating multiple foci of sebaceous differentiation. To evaluate twophase helical computed tomography ct in the characterization of salivary gland tumors.
119 461 1566 1373 215 1493 533 1506 375 296 871 1419 605 789 196 74 1089 37 835 281 243 1533 1003 676 885 167 939 785 1293 1365 1292 502 509 103 1431 565 996